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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BARD1 All Species: 13.03
Human Site: S410 Identified Species: 28.67
UniProt: Q99728 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99728 NP_000456.2 777 86648 S410 S Y R R V M S S P S A M K L L
Chimpanzee Pan troglodytes XP_526019 777 86498 S410 S Y R R V M S S P S A V K L L
Rhesus Macaque Macaca mulatta XP_001084740 777 86841 S410 S Y R R V M S S P S A M K L L
Dog Lupus familis XP_852715 923 103188 A557 R M M S S P S A T K L S P N S
Cat Felis silvestris
Mouse Mus musculus O70445 765 84236 S397 T H R Q M M S S P S T V K L S
Rat Rattus norvegicus Q9QZH2 768 84530 K399 T H R Q M M S K P S T V K L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519813 231 26178
Chicken Gallus gallus NP_001026417 750 82934 A397 S P G S N P I A R R N Y K G E
Frog Xenopus laevis NP_001082131 772 86896 K400 N S A K L G Q K S T A M P I S
Zebra Danio Brachydanio rerio XP_001921099 334 36093
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001188296 940 102732 G467 Q K R R L S G G R I R I S L S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 95.3 68.3 N.A. 69.5 68.5 N.A. 22.5 51.6 47.3 22.1 N.A. N.A. N.A. N.A. 26.8
Protein Similarity: 100 99.7 97.5 74.4 N.A. 81 80.9 N.A. 26.7 67.9 62.8 31.6 N.A. N.A. N.A. N.A. 41.4
P-Site Identity: 100 93.3 100 6.6 N.A. 53.3 46.6 N.A. 0 13.3 13.3 0 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 100 100 13.3 N.A. 86.6 80 N.A. 0 20 46.6 0 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 0 19 0 0 37 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 10 10 10 0 0 0 0 0 10 0 % G
% His: 0 19 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 0 0 10 0 10 0 10 0 % I
% Lys: 0 10 0 10 0 0 0 19 0 10 0 0 55 0 0 % K
% Leu: 0 0 0 0 19 0 0 0 0 0 10 0 0 55 28 % L
% Met: 0 10 10 0 19 46 0 0 0 0 0 28 0 0 0 % M
% Asn: 10 0 0 0 10 0 0 0 0 0 10 0 0 10 0 % N
% Pro: 0 10 0 0 0 19 0 0 46 0 0 0 19 0 0 % P
% Gln: 10 0 0 19 0 0 10 0 0 0 0 0 0 0 0 % Q
% Arg: 10 0 55 37 0 0 0 0 19 10 10 0 0 0 0 % R
% Ser: 37 10 0 19 10 10 55 37 10 46 0 10 10 0 46 % S
% Thr: 19 0 0 0 0 0 0 0 10 10 19 0 0 0 0 % T
% Val: 0 0 0 0 28 0 0 0 0 0 0 28 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 28 0 0 0 0 0 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _